RTÉ News & Current Affairs Managing Director Ed Mulhall has decided to step aside from his role for the duration of the BAI inquiry into the circumstances that led to false allegations being made against Fr Kevin Reynolds by RTÉ.
Editor of Current Affairs Ken O'Shea will also step aside for the duration of the inquiry.
Prime Time Investigates Executive Producer Brian Páircéir and reporter Aoife Kavanagh will not be involved in any on-air programming for this period.
Yesterday, the Cabinet requested an independent inquiry into the incident by the Broadcasting Authority of Ireland.
It will report back in two months' time.
An RTÉ statement said Mr Mulhall made the decision to step aside by agreement with RTÉ Director General Noel Curran.
"These decisions have been agreed in order to remove any possible doubt about the objectivity and impartiality of RTÉ's News and Current Affairs services at this time and are taken without prejudice to any party."
Last week, Fr Reynolds was awarded undisclosed damages and received an apology after RTÉ wrongly accused him of sexually abusing a girl and fathering a child in Kenya.
The next series of the Prime Time Investigates programme has been deferred until editorial reviews have been completed.
This evening, the Board of RTÉ decribed the situation as the most serious editorial question that has arisen since the late 1960s.
Minister for Communications Pat Rabbitte said the defamation of Fr Kevin Reynolds by RTÉ has raised grave issues.
Speaking on Morning Ireland, Mr Rabbitte said he could not remember a lapse of such magnitude. He said public anxieties had to be addressed.